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Researchers found 53 existing drugs that may keep the Ebola virus from entering human cells, a key step in the process of infection, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and the National Institutes of Health (NIH), and published today in the Nature Press journal Emerging Microbes and Infections. Among the better known drug types shown to hinder infection by an Ebola virus model: several cancer drugs, antihistamines and antibiotics. Among the most effective at keeping the virus out of human cells were microtubule inhibitors used to treat cancer. "In light of the historic and devastating outbreak of Ebola virus disease, there is an urgent need to rapidly develop useful treatments against Ebola infection, and our study results argue that repurposing existing drugs may be among the fastest ways to achieve this," said lead author Adolfo García-Sastre, PhD, Director of the Global Health and Emerging Pathogens Institute wit...

Dr. Deborah Anderson from Boston University School of Medicine (BUSM) and her colleagues are challenging dogma about the transmission of the human immunodeficiency virus type 1 (HIV-1). Most research has focused on infection by free viral particles, while this group proposes that HIV is also transmitted by infected cells. While inside cells, HIV is protected from antibodies and other antiviral factors, and cell-to-cell virus transmission occurs very efficiently through intercellular synapses. The Journal of Infectious Diseases (JID) has devoted their December supplement to this important and understudied topic. The 10 articles, four from researchers at BUSM, present the case for cell-associated HIV transmission as an important element contributing to the HIV epidemic. Anderson chides fellow researchers for not using cell-associated HIV in their transmission models: "The failure of several recent vaccine and microbicide clinical trials to prevent HIV transmission may be due in p...

Local authorities on Wednesday announced the suspension of classes in a school in south China's Guangdong Province after 140 students were infected by Norovirus. Norovirus is a contagious virus that can infect anyone, which can be got from an infected person, contaminated food or water or by touching contaminated surfaces. It is the most common cause of viral gastroenteritis in humans and affects people of all ages. Symptoms of the highly-contagious stomach virus include vomiting, diarrhoea, fever and body aches, typically patients recover within several days. Grade I and II students of Shenzhen Baihe Foreign Language School began showing signs of food poisoning after experiencing stomach aches and vomiting on Monday afternoon. The local authorities said that by Tuesday morning, 140 students out of the school's 1,400, showed similar symptoms. An investigation by the local disease prevention and control centre showed the mass vomiting was caused by Norovirus in...

A middle-aged woman alleged to be a witch in Ughelli South local government area of Delta (name withheld) on Friday evening confessed to using her urine to mix the beans with which she prepared moi-moi which she sold to members of the public as well as fed family members with. LeadershipNG reports that the woman, well-known in the community for her beauty and well-prepared meals especially her moi-moi that she sold to unsuspecting members of the public, allegedly confessed when she was almost lynched by an angry mob over allegations by a young man in the area that she planned to kill him with her witchcraft. It was gathered that the young man was about taking his bath in the bathroom when a rat almost hit him on the leg. On seeing the rat, he picked a piece of wood and kill it, but instead of beating a retreat, the rat allegedly increased in size, eventually turning into a human being before disappearing, leaving two slippers behind. The young man was said to have gone to to...

A suicide bomber was the only one to die in a failed attempt to attack the Evangelical Church of West Africa, ECWA (pictured above), at Tudunwada in Gombe on the 1st of January 2015. According to reports, the suicide bomber arrived the church at about 8am in a motorcycle and attempted to forcefully drive into the premises which was parked full of worshipers as the church was holding its new year celebration service. As he made to enter, the suicide bomber was stopped by members of the church's Boys Brigade stationed at the entrance of the church for security purpose. The bomb on him immediately exploded, killing him and injuring 8 others who were immediately rushed to the hospital for medical attention. This attack came barely 24hours after two suicide bombers attempted to attack the Army barracks in Gombe state on New years eve. Reports say the suicide bombers arrived the military check point leading to the barracks at about 8pm and in the course of waiting to be search...

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